USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P48059 USC-OGP 2-DE database:  P48059 P48059 General information about the entry View entry in simple text format Entry name LIMS1_HUMAN Primary accession number P48059 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=LIM and senescent cell antigen-like-containing domain protein 1; AltName: Full=Particularly interesting new Cys-His protein 1; Short=PINCH-1; AltName: Full=Renal carcinoma antigen NY-REN-48;. Gene name Name=LIMS1 Synonyms=PINCH, PINCH1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0988: pI=8.72; Mw=28695 Cross-references UniProtKB/Swiss-Prot P48059; LIMS1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LIMS1_HUMAN Primary accession number P48059 Secondary accession number(s) B2RAJ4 B7Z483 B7Z7R3 B7Z907 Q53TE0 Q9BS44 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 176) Name and origin of the protein Description RecName: Full=LIM and senescent cell antigen-like-containing domain protein 1; AltName: Full=Particularly interesting new Cys-His protein 1; Short=PINCH-1; AltName: Full=Renal carcinoma antigen NY-REN-48; Gene name Name=LIMS1 Synonyms=PINCH, PINCH1 Encoded on Name=LIMS1; Synonyms=PINCH, PINCH1 Keywords 3D-structure; Acetylation; Alternative splicing; Cell junction; Cell membrane; Complete proteome; Direct protein sequencing; LIM domain; Membrane; Metal-binding; Reference proteome; Repeat; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U09284; AAA20086.2; -; mRNA EMBL AK296992; BAH12469.1; -; mRNA EMBL AK302411; BAH13699.1; -; mRNA EMBL AK304260; BAH14143.1; -; mRNA EMBL AK314217; BAG36891.1; -; mRNA EMBL AC010095; AAY14983.1; -; Genomic_DNA EMBL AC012487; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC005341; AAH05341.1; -; mRNA CCDS CCDS2078.1; -. [P48059-1]; . CCDS CCDS54382.1; -. [P48059-2]; . CCDS CCDS54383.1; -. [P48059-4]; . CCDS CCDS54384.1; -. [P48059-5]; . CCDS CCDS54385.1; -. [P48059-3]; . PIR JC2324; JC2324; . RefSeq NP_001180411.1; NM_001193482.1. [P48059-4]; . RefSeq NP_001180412.1; NM_001193483.2. [P48059-2]; . RefSeq NP_001180413.1; NM_001193484.1. [P48059-5]; . RefSeq NP_001180414.1; NM_001193485.2. [P48059-3]; . RefSeq NP_001180417.1; NM_001193488.1. [P48059-1]; . RefSeq NP_004978.2; NM_004987.5. [P48059-1]; . UniGene Hs.597715; -; . UniGene Hs.613268; -; . PDB 1G47; NMR; -; A=1-70 PDB 1NYP; NMR; -; A=188-251 PDB 1U5S; NMR; -; B=188-251 PDB 2COR; NMR; -; A=125-190 PDB 2D8X; NMR; -; A=71-127 PDB 2KBX; NMR; -; B=1-70 PDB 3F6Q; X-ray; 1.60 A; B=6-68 PDB 4HI8; X-ray; 1.20 A; B=6-68 PDB 4HI9; X-ray; 1.20 A; B=6-68 PDBsum 1G47; -; . PDBsum 1NYP; -; . PDBsum 1U5S; -; . PDBsum 2COR; -; . PDBsum 2D8X; -; . PDBsum 2KBX; -; . PDBsum 3F6Q; -; . PDBsum 4HI8; -; . PDBsum 4HI9; -; . ProteinModelPortal P48059; -; . SMR P48059; -; . BioGrid 110175; 37; . DIP DIP-40671N; -; . IntAct P48059; 38; . MINT MINT-5004275; -; . STRING 9606.ENSP00000446121; -; . iPTMnet P48059; -; . PhosphoSitePlus P48059; -; . BioMuta LIMS1; -; . DMDM 18266876; -; . OGP P48059; -; . EPD P48059; -; . MaxQB P48059; -; . PaxDb P48059; -; . PeptideAtlas P48059; -; . PRIDE P48059; -; . DNASU 3987; -; . Ensembl ENST00000332345; ENSP00000331775; ENSG00000169756. [P48059-1]; . Ensembl ENST00000338045; ENSP00000337598; ENSG00000169756. [P48059-3]; . Ensembl ENST00000393310; ENSP00000376987; ENSG00000169756. [P48059-1]; . Ensembl ENST00000409441; ENSP00000387264; ENSG00000169756. [P48059-5]; . Ensembl ENST00000410093; ENSP00000386926; ENSG00000169756. [P48059-4]; . Ensembl ENST00000544547; ENSP00000437912; ENSG00000169756. [P48059-2]; . GeneID 3987; -; . KEGG hsa:3987; -; . UCSC uc002teg.4; human. [P48059-1]; . CTD 3987; -; . DisGeNET 3987; -; . GeneCards LIMS1; -; . HGNC HGNC:6616; LIMS1; . HPA HPA058455; -; . HPA HPA061230; -; . MIM 602567; gene; . neXtProt NX_P48059; -; . OpenTargets ENSG00000169756; -; . PharmGKB PA30389; -; . eggNOG KOG2272; Eukaryota; . eggNOG ENOG410XP46; LUCA; . GeneTree ENSGT00760000118910; -; . HOGENOM HOG000253950; -; . HOVERGEN HBG000053; -; . InParanoid P48059; -; . OMA HFNCTAC; -; . OrthoDB EOG091G08K3; -; . PhylomeDB P48059; -; . TreeFam TF314113; -; . Reactome R-HSA-446353; Cell-extracellular matrix interactions; . Reactome R-HSA-446388; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components; . ChiTaRS LIMS1; human; . EvolutionaryTrace P48059; -; . GeneWiki LIMS1; -; . GenomeRNAi 3987; -; . PRO PR:P48059; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000169756; -; . CleanEx HS_LIMS1; -; . ExpressionAtlas P48059; baseline and differential; . Genevisible P48059; HS; . GO GO:0005911; C:cell-cell junction; IMP:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell; . GO GO:0019901; F:protein kinase binding; IPI:UniProtKB; . GO GO:0008270; F:zinc ion binding; IDA:UniProtKB; . GO GO:0007569; P:cell aging; TAS:ProtInc; . GO GO:0034329; P:cell junction assembly; TAS:Reactome; . GO GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB; . GO GO:0045184; P:establishment of protein localization; IMP:UniProtKB; . GO GO:0045892; P:negative regulation of transcription; DNA-templated; IDA:UniProtKB GO GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:UniProtKB; . GO GO:0051894; P:positive regulation of focal adhesion assembly; IMP:UniProtKB; . GO GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB; . GO GO:0043547; P:positive regulation of GTPase activity; IMP:UniProtKB; . GO GO:1900026; P:positive regulation of substrate adhesion-dependent cell spreading; IMP:UniProtKB; . Gene3D 2.10.110.10; -; 5; . InterPro IPR017351; PINCH; . InterPro IPR001781; Znf_LIM; . PANTHER PTHR24210; PTHR24210; 1; . Pfam PF00412; LIM; 5; . PIRSF PIRSF038003; PINCH; 1; . SMART SM00132; LIM; 5; . PROSITE PS00478; LIM_DOMAIN_1; 4; . PROSITE PS50023; LIM_DOMAIN_2; 5; .

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